Dementia in patients with atrial fibrillation and the value. He is also a senior scientist at londons lawson health research institute. The hachinski ischaemic score his was first introduced in 1975 as a clinical scale intended to differentiate cases of dementia resulting from multiple strokes multi. Eligible patients were randomized to either the medical or surgical arm from a computergenerated algorithm. In patients with atrial fibrillation, these rates ranged from 55% 95% ci 3277 to 69% 95% ci 3991%. Vladimir hachinski is a canadian clinical neuroscientist and researcher based at the schulich school of medicine and dentistry at western university. The goal of this study is to examine the utility of the hachinski ischemic scale his in identifying cognitive dysfunction and diagnosis of. Our objectives were to investigate the utility of the hachinski ischemic score his in differentiating patients with pathologically verified alzheimers disease ad, multiinfarct dementia mid, and mixed ad plus cerebrovascular disease dementia, and to identify the specific items of the his that best discriminate those dementia subtypes. Modified hachinski ischemic scale nacc version mhisnacc modified medical research council dyspnea scale mmrc modified rankin scale mrs movement disorder society version of the unified parkinsons disease rating scale mdsupdrs ms quality of life 54 msqol54. The construct validity of the ischemic score of hachinski. Click on the image or right click to open the source website in a new browser window. Multiinfarct dementia mid may be the second most common form of dementia in later life. In patients in whom the diagnosis of dementia was excluded, the hachinski ischemic score suggested the presence of vascular dementia in 11% and mixed dementia in 30%.
Diagnostic and statistical manual of mental disorders dsmiii, ed 3. Objective to consolidate and further validate the his. Clinical correlates of hachinski ischemic score and. A commonly used aid in the clinical diagnosis of mid is the hachinski ischaemic score his. Started in 1995, this collection now contains 6769 interlinked topic pages divided into a tree of 31 specialty books and 732 chapters. The sensitivity and specificity of hachinski s ischaemic score is in the diagnosis of the vascular aetiology of dementia was studied in a series of 32 demented patients, dementia of the alzheimer type 16, multiinfarct dementia 7, mixed dementia 6, picks disease 3, with neuropathological diagnosis as the point of reference. One of the main advantages of the ischemic score is that it is simple and used widely more than 2300 citations, providing a standard of comparison.
The hachinski ischemic score his is known to be a simple clinical tool, posted in neurology tagged acv, demencia, dementia, escala, hachinski, his. Design the canadian study for health and aging was used for this study. Optimizing the hachinski ischemic scale citeseerx penn state. Prospective neuropathological validation of hachinskis.
Criteria for rating the items of the his were never given, or interobserver reliability in applying it has never been tested. Hachinski ischaemia score hachinski vc, iliff ld, zilkha e, et al. The eponymic hachinski ischemic score his is now a standard means for identifying the treatable components of dementia. Patients scoring 7 or greater are classified as having multiinfarct dementia, and patients scoring. Researchers have recognised the utility of the his as a tool to differentiate ischemic forms of.
The validity of hachinski ischemic score his in differentiating between alzheimers disease ad and vascular dementiavad has been questioned and compared with the gold standard autopsy. Optimizing the hachinski ischemic scale cerebrovascular. The aim of this study is to investigate the relationship between hachinski ischemic score his and vascular factors as well as between his and the cognitive function in elderly community. A low hachinski ischemic score is less likely to indicate vascular dementia because ischemic lesions severe enough to produce a dementia. Pdf use of hachinski ischemic score in the memory clinic. What contribution can the hachinski ischemic scale make to. Hachinskis ischemic score and the diagnosis of vascular dementia. Modified hachinski ischemic scale nacc version mhisnacc. Born in ukraine, he reached canada by way of venezuela, where his parents emigrated to escape stalin. Analysis of patients with pathologically verified dementias. Hachinski ischemic scale and proportions of vascular and nonvascular. Its conceptual basis rests on the view that vascular dementia is the result of strokes, not of general atherosclerosis or ischaemia. Hachinski ischemic scale his was originally developed to establish a relationship between cerebral blood flow and dementia.
Analysis of patients with pathologically verified dementias j. Modified hachinski ischemic scale nacc version cdisc. The hachinski ischemic score his scale is a simple clinical tool proposed and. Diagnostic and treatment centre criteria and the hachinski ischemic score. Sep 19, 20 modified hachinski ischemic scale nacc version mhisnacc modified medical research council dyspnea scale mmrc modified rankin scale mrs.
Titheradge, daniel, isaac, mokhtar, bremner, stephen and tabet, naji 2020 cambridge cognitive examination and hachinski ischemic score as predictors of mri confirmed pathology in dementia. To confirm that the his can be used to differentiate related vad from ad in a thai population. The minimental state examination was used to assess the accuracy of the medicalchart diagnoses of dementia. Hachinski ischemic score his is a simple and valid clinical tool used for differentiating multiinfarct dementia mid form alzheimers disease. Two hundred fortyone nursing home patients from the national nursing home survey pretest were assessed using the ischemic score of hachinski. The sensitivity and specificity of hachinskis ischaemic score is in the diagnosis of the vascular aetiology of dementia was studied in a series of 32 demented patients, dementia of the alzheimer type 16, multiinfarct dementia 7, mixed dementia 6, picks disease 3, with neuropathological diagnosis as the point of reference.
Pathological verification of ischemic score in differentiation of dementias. The canadian study for health and aging was used for this study. The hachinski ischemic scale his was introduced in 1975 to standardize the differential diagnosis between mid and primary degenerative dementia hachinski et al. Mhis abbreviation stands for modified hachinski ischemia scale. The dsmiv criteria have good sensitivity, but low specificity, but the nindsairen criteria are the most specific of all available criteria and are used most commonly in research see table. Response by sposato et al to letter regarding article. All subjects included in the trial were evaluated with. Moroney neurogical institute, columbia university, new york, new york 10032, usa. In order to ensure no ethnic biases towards mci diagnoses were. P1008 clinical characteristics and hachinski ischemic.
Mar 02, 2020 the hachinski ischemic score his is known to be a simple clinical tool, currently used for differentiating major types of dementia, such as primary degenerative. Framingham coronary heart disease risk score, hachinski ischemic score his, clinical dementia rating cdr. Use of hachinski ischemic score in the memory clinic. The hachinski ischemic score his scale is a simple clinical tool proposed and currently used for differentiating types of dementia primary degenerative, vascular or multiinfarct, mixed type. The hachinski ischemic score his is known to be a simple clinical tool, currently used for differentiating major types of dementia, such as primary degenerative.
Though there have been developments of newer tools for differentiating types of dementia, his has continuously and widely been used for such purpose 1, 3, 4. Atrial fibrillation and the hachinski ischemic scalereply. Hachinskis ischemic score and the diagnosis of vascular. Table 1 original and revised scorings ofthe ischaemic scale.
Cambridge cognitive examination and hachinski ischemic. Ist3 expert reading panel and the ist3 collaborative group. Pdf the validity ofhachinski ischemic score his in differentiating between alzheimers disease ad and vascular dementia vad has been questioned. We wonder whether it would not be simpler to add to the ischemic score a statement whether atrial fibrillation is present, and if. The construct validity of the ischemic score of hachinski for. I the hachinski ischemic score, commonly abbreviated his, is a simple items clinical tool used for differentiating types of dementia primary degenerative, vascular or multiinfarct, mixed type. A distinguished university professor of neurology at western university, dr.
His research pertains in the greatest part to stroke and dementia, the interactions between them and their joint prevention. Hachinski has written, cowritten, or coedited 17 books and more than 800 frequently cited scientific publications. Demographic characteristics, such as sex, age, education, history of drinking and smoking, family history of dementia and stroke, diabetes mellitus, hypertension, hyperlipidemia, cardiovascular disease. Medical chart diagnoses were used to classify those with and without dementia. The norms provided by the manual were utilised for nonhispanic whites. He is a leading advocate, contributor and thought leader of the vascular treatable component of dementia, crystallizing the concepts and coining the terms multiinfarct dementia, leukoaraiosis, brain at risk stage, vascular cognitive impairment, devising the eponymic ischemic score that identifies the treatable component over 3700 citations. Modified hachinski ischemia scale how is modified hachinski ischemia scale abbreviated. Diagnostic evaluation of degenerative and vascular. This objective evaluation scale consists of items for systematic registration of anamnestic information, present complaints and medical examination findings fig. Hachinski vc, iliff ld, zilhka e, du boulay gh, mcallister vl, marshall j, russell rw, symon l. Hachinski ischaemia score, hachinski ischemia score, hachinski ischemia score assessment scale.
Patients with a score of 7 or higher are more likely to have a vascular dementia. It was a cohort study conducted in 3 waves in 1991, 19961997, and 20012002. Misclassification of dementia subtype using the hachinski. Clinical correlates of hachinski ischemic score and vascular factors in cognitive function of elderly. Hachinski ischemic score definition of hachinski ischemic. Inclusion criteria also included a score of 0 to 23 on the minimental state examination mmse, disease duration of more than 2 months, onset of the disease at age less than 80 years, and the availability of a reliable caregiver. Among the subgroups of the vascular dementia vad, subcortical vascular dementia svad is the most common and has somewhat different clinical. A low hachinski ischemic score is less likely to indicate vascular dementia because ischemic lesions severe enough.
These images are a random sampling from a bing search on the term hachinski ischemia score. Vascular risk as a predictor of cognitive decline in a cohort of. Prospective neuropathological validation of hachinskis ischaemic. He qualified in toronto, where he later set up, with john w norris, the worlds first successful acute stroke unit.
View the article pdf and any associated supplements and figures for a period of 48 hours. Hachinski has written, cowritten, or coedited 17 books and. The hachinski ischemic score his is the questionnaire most commonly used for diagnosis of vascular dementia. Modified hachinski score for vascular dementia the soapnote. Variability in scoring the hachinski ischaemic score age. He is also a senior scientist at london s lawson health research institute. Clinical correlates of hachinski ischemic score and vascular. The hachinski ischemic score his is known to be a simple clinical tool, currently used for differentiating major types of dementia, such as primary degenerative, vascular or multiinfarct, and mixed type 1, 2. Misclassification of dementia subtype using the hachinski ischemic score. However, the studies which estimated the validity of this scale in. Dementia in patients with atrial fibrillation and the. His was originally developed to establish a relationship between cerebral blood flow and dementia. While this link is well established in the literature, implementing this work in primary care settings remains a challenge.
Pdf prospective neuropathological validation of hachinskis. We wonder whether it would not be simpler to add to the ischemic score a statement whether atrial fibrillation is present, and if so, whether it was treated. Diagnostic evaluation of degenerative and vascular dementia. Mar 19, 2019 the hachinski ischemic score his is known to be a simple clinical tool, currently used for differentiating major types of dementia, such as primary degenerative.
Modified hachinski ischemia scale how is modified hachinski. The hachinski ischemic score his is known to be a simple clinical tool, posted in neurology tagged. What is the abbreviation for modified hachinski ischemia scale. Jul 04, 2019 the hachinski ischemic score his is known to be a simple clinical tool, currently used for differentiating major types of dementia, such as primary degenerative. Modified hachinski score for vascular dementia the. The usefulness of this score is controversial, and we hypothesized that this is because many items of the his are open to a wide range of interpretations. The accuracy of the ischemic score is of hachinski in the differential diagnosis between senile dementia sdat and multiinfarct dementia mid is evaluated in this study.